Clinical Study Title:
Yridoxine improves endothelial function in cardiac transplant recipients.

Plain English Summary:

Elevated homocysteine levels are also associated with endothelial dysfunction, which is a common occurrence in patients who have had heart transplants. This study looked at the use of folate and vitamin b6 supplements on the endothelial dysfunction. Participants in this study received a vitamin b6 supplement, a folate supplement, or a placebo supplement post surgery. At the conclusion of the study, the participants who had been given the vitamin b6 supplements had improved endothelial functioning. This suggests that a supplement including vitamin b6 can help to improve endothelial functioning, especially for heart transplant patients.

Authors

Miner SE. Cole DE. Evrovski J. Forrest Q. Hutchison S. Holmes K. Ross HJ.

Institution

Department of Medicine, University of Toronto, Toronto, Ontario, Canada.

Country of Publication

United States

Source

Journal of Heart & Lung Transplantation. 20(9):964-9, 2001 Sep.